Tragic Plane Crash in Louisville Claims Seven Lives

Wed Nov 05 2025 11:18:48 GMT+0200 (Eastern European Standard Time)

A UPS cargo plane disaster during takeoff in Louisville, Kentucky has resulted in the deaths of at least seven individuals, with numerous others injured. The incident raises safety concerns and highlights the impact on the local community.

In a tragic incident, a UPS cargo plane crashed shortly after taking off from Louisville Muhammad Ali International Airport, claiming at least seven lives, including likely deaths among the crew. The plane, en route to Honolulu, exploded upon departure, leaving thick smoke and significant damage to nearby businesses. The incident has prompted an ongoing investigation and raised alarms about potential safety risks in the area.

Seven people were killed when a UPS cargo plane crashed while taking off from an airport in Louisville, Kentucky on Tuesday evening, the state's governor said.

At least 11 other people were injured when the freight plane exploded as it departed Louisville Muhammad Ali International Airport at around 17:15 local time, sending thick plumes of black smoke into the sky. Kentucky Governor Andy Beshear said the plane's three crew members were likely to be among the dead, adding that, Anyone who has seen the images and the video knows how violent this crash is.

Officials warned that people suffered very significant injuries in the incident and the death toll could rise.

UPS flight 2976 bound for Honolulu, Hawaii was carrying 38,000 gallons of fuel when it skidded off the runway in Louisville and struck nearby buildings. The explosion engulfed at least two nearby businesses, including a petroleum recycling company. A shelter-in-place order was initially issued for within five miles of the airport due to concerns of further explosions and air pollution, but was later reduced to just one mile.

All departing flights for the evening were cancelled, the airport said in a statement on social media.

Louisville Fire Department Chief Brian O'Neill reported that the fire has almost been contained. He emphasized that numerous personnel were tasked with surrounding and controlling the large-scale incident.

Governor Beshear urged people to avoid the crash site, cautioning of lingering explosive materials. The NTSB has taken over the investigation, with a team scheduled to arrive in Kentucky for further inquiries.

The cargo aircraft involved was an MD-11F, originally a passenger jet, transferred to UPS in 2006. This incident marks a significant tragedy for Louisville, a city closely tied to UPS, as residents concern themselves for their loved ones within the company.

UPS expressed its deep sorrow over the incident and has suspended operations at its local hub.

Louisville Mayor, Craig Greenberg, referred to the crash as an incredible tragedy that would remain in the community's memory for years to come.