US news anchor Savannah Guthrie has posted a video message tearfully pleading for the return of her abducted mother and seeking proof from her captors that the 84-year-old is still alive.

We want to hear from you and we are ready to listen, the NBC host says, flanked by her siblings in the clip posted to Instagram. Please reach out to us.

Nancy Guthrie went missing in the middle of the night from her home in Arizona over the weekend. Authorities suspect she was kidnapped and are working with the FBI to authenticate a ransom note.

We need to know without a doubt that she is alive and that you have her, said Savannah in the video. Her message stressed that they are willing to engage and plead for clarification on her mother's safety.

Pima County Sheriff's Office indicated they were still speaking with anyone who had contact with Nancy Guthrie last weekend, but no suspect has been identified. In her emotional appeal, Savannah noted her mother’s health condition, underscoring the urgency of the situation due to her need for medication.

Selena mentioned how much they miss their mother and the estimates of her current health situation, saying, Her health, her heart is fragile. She lives in constant pain. She needs it to survive. She needs it not to suffer.

In response to the public crisis, US President Donald Trump issued a statement promising federal assistance, saying, I spoke with Savannah Guthrie, and let her know that I am directing ALL Federal Law Enforcement to be at the family's, and Local Law Enforcement's, complete disposal, IMMEDIATELY.

Authorities and the community remain actively engaged in searching for Nancy Guthrie, showcasing the collective urgency surrounding the case.